Women at greater risk for osteoporosis fracture may also reach different decisions about extended AI therapy based on these trade offs cheapest cialis available recently employed an RNase FISH protocol with multiplex ligation dependent probe amplification to demonstrate that the FISH signals being interpreted as ESR1 amplification were sensitive to RNase treatment, indicating that FISH was detecting accumulation of ESR1 transcripts in cells expressing high levels of ER RNA, rather than gene amplification 40